I believe that most, if not all, major EN>IT IT>EN dictionaries are now available on CD-ROM or at least with CD-ROM available (in addition to the paper dictionary).
I don’t have a link for the Ragazzini (Zanichelli), but the Picchi (Hoepli), Rizzoli-Larousse "Sansoni" (which, sadly, does not contain the full text of the great Sansoni-Macchi), and Hazon-Garzanti are now available online.
Of the
